The Ideas of Ludwik Fleck and Their Application to the Eukaryotic Cell Cycle, the Restriction Point, and G1-phase Control
نویسندگان
چکیده
The ideas of Ludwik Fleck (1896-1961) analyzing the conservative nature of scientific ideas are discussed and applied to the proposed G1-phase restriction point as a regulatory element of the mammalian cell cycle. Fleck proposed that ideas become fixed and difficult to change because criticisms of current and dominant models are either ignored or turned to support of the current model. The idea of a thought-collective leading to the stability of ideas is a central theme of the ideas of Ludwik Fleck.
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